πŸ“‹Urology CPT Codes Reference

What This MOC Covers

This reference index covers the major CPT code families in Urology β€” organized by anatomic region and procedure type. Use this note to navigate to individual procedure notes, identify correct code selection within a family, understand bundling rules, and locate modifier and global period guidance. All codes fall under the Surgery β€” Urinary System CPT section (50010-53899) unless otherwise noted.


πŸ’° Kidney β€” Incision and Drainage

CPTDescriptionNotes
50010Renal exploration, not necessitating other specific proceduresRare β€” exploration without definitive procedure
50020Drainage of perirenal or renal abscess, openOpen drainage; percutaneous alternative is 50021
50021Drainage of perirenal or renal abscess, percutaneousIR-guided; code includes imaging guidance
50040Nephrostomy, nephrotomy with drainageOpen drainage of kidney
50045Nephrotomy with explorationExploration + drainage; no stone removal
50060Nephrolithotomy; removal of calculusStone removal, open
50065Nephrolithotomy; secondary surgical operationReoperation same kidney
50070Nephrolithotomy; complicated by congenital kidney abnormalityHorseshoe kidney, ectopic, etc.
50075Nephrolithotomy; removal of large staghorn calculusStaghorn β€” branched calculus filling collecting system
50080Percutaneous nephrostolithotomy, up to 2 cmPCNL β€” smaller stone
50081Percutaneous nephrostolithotomy, over 2 cmPCNL β€” larger stone; higher complexity

πŸ§‘πŸΎβ€βš•οΈ Kidney β€” Excision (Nephrectomy Family)

CPTDescriptionGlobalwRVU
50220Nephrectomy, open, simple090~16.0
50225Nephrectomy, open, complicated (prior surgery)090~19.0
50230Radical nephrectomy, open, with regional lymphadenectomy and/or vena caval thrombectomy090~23.81
50234Radical nephrectomy with total ureterectomy, transperitoneal, with LND090~24.0
50236Radical nephrectomy with total ureterectomy090~22.0
50240Partial nephrectomy, open090~20.0
50543Laparoscopic partial nephrectomy090~20.0
50545Laparoscopic radical nephrectomy090~20.0
50546Laparoscopic radical nephrectomy with regional lymphadenectomy090~22.0
50548Laparoscopic nephrectomy with total ureterectomy090~22.0

Key distinction: Use open codes (50220-50240) for open approaches. Use laparoscopic codes (50543-50548) for minimally invasive. Do not mix open and laparoscopic descriptors.


Kidney β€” Repair and Transplant

CPTDescriptionNotes
50300Donor nephrectomy, open, from cadaver donorProcurement
50320Donor nephrectomy, open, from living donorLiving donor open
50323Backbench reconstruction β€” arterial anastomosisGraft preparation
50325Backbench reconstruction β€” venous anastomosisGraft preparation
50327Backbench reconstruction β€” ureteral anastomosisGraft preparation
50329Backbench reconstruction β€” each additionalAdd-on code
50340Recipient nephrectomy, separate procedurePre-transplant native kidney removal
50360Renal allotransplantation, no recipient nephrectomyTransplant only
50365Renal allotransplantation with recipient nephrectomyTransplant + native removal
50370Removal of transplanted renal allograftExplant of failed transplant
50380Renal autotransplantationReplanting patient’s own kidney

Kidney β€” Laparoscopic and Endoscopic

CPTDescription
50541Laparoscopic ablation of renal cysts
50542Laparoscopic ablation of renal mass lesion
50543Laparoscopic partial nephrectomy
50544Laparoscopic pyeloplasty
50545Laparoscopic radical nephrectomy
50546Laparoscopic radical nephrectomy with lymphadenectomy
50547Laparoscopic donor nephrectomy, living donor
50548Laparoscopic nephrectomy with total ureterectomy
50549Unlisted laparoscopic procedure, renal

Kidney β€” Introduction and Drainage (Percutaneous/Endoscopic)

CPTDescriptionNotes
50382Removal and replacement of externalized ureteral stentVia established tract
50384Removal of internalized ureteral stent via percutaneous approachFluoroscopic guidance
50385Removal of internalized ureteral stent via transurethral approachCystoscopic
50386Removal of internalized ureteral stent via transurethral approach, without imagingOffice-based
50390Aspiration and/or injection of renal cyst or pelvisPercutaneous
50391Instillation of therapeutic agent into renal pelvisVia nephrostomy tube
50395Introduction of guide into renal pelvis for dilationRenal tract dilation
50396Manometric studies through nephrostomyPressure studies
50398Change of nephrostomy or pyelostomy tubeTube exchange

Renal Pelvis and Ureteropelvic Junction

CPTDescription
50400Pyeloplasty, simpleOpen UPJ repair
50405Pyeloplasty, complicatedSecondary or complex UPJ repair
50430Injection procedure for antegrade nephrostoureterographyDiagnostic
50431Injection procedure with urodynamic evaluationWith pressure studies
50432Placement of nephrostomy catheter, percutaneousInitial placement
50433Placement of nephroureteral catheter, percutaneousCrosses UPJ
50434Convert nephrostomy catheter to nephroureteral catheterCatheter exchange
50435Exchange of nephrostomy catheterRoutine tube exchange

Ureter β€” Incision, Excision, Repair

CPTDescriptionNotes
50600Ureterotomy with exploration or drainage, openOpen ureter exploration
50605Ureterotomy for insertion of indwelling stentOpen stent placement
50610Ureterolithotomy, upper one-third of ureterOpen stone removal
50620Ureterolithotomy, middle one-thirdOpen stone removal
50630Ureterolithotomy, lower one-thirdOpen stone removal
50650Ureterectomy, with bladder cuff, unilateralPartial ureterectomy
50660Ureterectomy, total, ectopic ureter; combined abdominal, vaginal approachComplete ureter removal
50700Ureteroplasty, plastic operation on ureterRepair/reconstruction
50706Balloon dilation, ureteral stricture, endoscopicEndoscopic stricture treatment
50710Ureterolysis, with or without repositioning of ureterRetroperitoneal fibrosis release
50715Ureterolysis, with or without repositioning, complicatedWith vascular or bowel involvement
50722Ureterolysis for ovarian vein syndromeSpecific ovarian vein compression
50725Ureterolysis for retrocaval ureterVena caval anomaly
50727Revision of urinary cutaneous diversionRevision of ileal conduit/stoma
50728Revision of urinary cutaneous diversion β€” additionalAdd-on
50740Ureteropyelostomy, anastomosis of ureter and renal pelvisOpen
50750UreterocalycostomyUreter to calyx anastomosis
50760UreteroureterostomyEnd-to-end or side-to-side ureteral anastomosis
50770TransureteroureterostomyCrossing anastomosis β€” one ureter to other
50780Ureteroneocystostomy; anastomosis of ureter to bladder, singleReimplantation
50782Ureteroneocystostomy; anastomosis of ureter to bladder, with bladder flapPsoas hitch / Boari flap
50783Ureteroneocystostomy; with extensive ureteral tailoringFor megaureter
50785Ureteroneocystostomy; combined with cystostomyWith bladder opening
50800Ureteroenteric anastomosis (direct or conduit)Ureteral to bowel anastomosis
50810UreterosigmoidostomyUreteral implantation into sigmoid
50820Ureteroileal conduit (Bricker procedure)Ileal conduit urinary diversion
50825Continent diversion, any typeContinent pouch construction
50830Urinary undiversionReversal of urinary diversion
50840Replacement of all or part of ureter by small intestineUreteral replacement
50845Cutaneous appendico-vesicostomyMitrofanoff-type channel
50860Ureterostomy, transplantation of ureter to skinCutaneous ureterostomy
50900Ureterorrhaphy, suture of ureter wound or injuryRepair of laceration
50940Deligation of ureterRelease of ligated ureter

Bladder β€” Incision and Drainage

CPTDescription
51020Cystotomy with fulguration and/or insertion of radioactive materialOpen bladder with treatment
51030Cystotomy with cryosurgical destruction of intravesical lesionCryotherapy via open
51040Cystostomy, cystotomy with drainageOpen bladder drainage
51045Cystotomy with insertion of ureteral catheterOpen ureteral catheterization
51050Cystolithotomy, cystotomy with removal of calculusOpen bladder stone removal
51060Transvesical ureterolithotomyStone removal through bladder
51065Cystotomy with calculus basket extraction or ultrasonic or electrohydraulic fragmentationFragmentation via open
51080Drainage of perivesical or prevesical space abscessOpen abscess drainage

Bladder β€” Excision

CPTDescriptionNotes
51500Excision of urachal cyst or sinusUrachal anomaly
51520Cystotomy, for simple excision of vesical neckBladder neck excision
51530Cystotomy for excision of bladder tumorOpen tumor excision
51550Cystectomy, partial, simplePartial bladder removal
51555Cystectomy, partial, complicatedComplex/prior radiation
51560Cystectomy, partial, with reimplantation of ureter(s) into bladderWith ureteral reimplant
51565Cystectomy, partial, with reimplantation of ureter(s) into bladder and urethroplastyWith urethral repair
51570Cystectomy, complete, simpleTotal cystectomy β€” female
51575Cystectomy, complete, with bilateral pelvic lymphadenectomyWith LND
51580Cystectomy, complete, with urethrectomy and ureteroenteric diversionTotal cystectomy + diversion
51585Cystectomy, complete, with urethrectomy, ureteroenteric diversion, with LNDFull radical cystectomy female
51590Cystectomy, complete, with ureteroenteric diversionMale cystectomy + diversion
51595Cystectomy, complete, with ureteroenteric diversion, with LNDRadical cystectomy male
51596Cystectomy, complete, with continent diversion, with LNDWith continent pouch
51597Pelvic exenteration, complete, for vesical, prostatic or urethral malignancyFull pelvic exenteration

Bladder β€” Introduction (Endoscopy/Cystoscopy)

CPTDescriptionNotes
51600Injection procedure for cystography or voiding urethrocystographyContrast study
51605Injection procedure with insertion of chain for cystourethrographyBead chain study
51610Injection procedure for retrograde urethrocystographyRetrograde study
51700Bladder irrigation, simple; lavage and/or instillationRoutine irrigation
51701Insertion of non-indwelling catheterStraight cath
51702Insertion of temporary indwelling bladder catheterFoley catheter
51703Insertion of temporary indwelling bladder catheter, complicatedDifficult catheterization
51705Change of cystostomy tube; simpleRoutine suprapubic change
51710Change of cystostomy tube; complicatedComplex change
51715Endoscopic injection of implant material into submucosal tissues of urethra/bladder neckBulkamid, Deflux, etc.
51720Bladder instillation of anticarcinogenic agentBCG, mitomycin C β€” via catheter
51725Simple cystometrogram (CMG)Urodynamics
51726Complex CMGWith EMG or voiding
51728CMG with voiding pressure studiesWith micturitional urethral pressure
51729CMG with voiding pressure and urethral pressure profileComplete urodynamics
51736Simple uroflowmetryFlow rate study
51741Complex uroflowmetryWith calibrated equipment
51784Electromyography of anal or urethral sphincter, otherEMG sphincter
51785Needle EMG of anal or urethral sphincter, otherNeedle EMG
51797Voiding pressure studies, intra-abdominalAbdominal pressure
51798Ultrasound post-void residual measurementPVR β€” can be performed by physician

Transurethral Surgery (Cystoscopy/TURBT/TURP)

CPTDescriptionNotes
52000CystourethroscopyDiagnostic cystoscopy
52001Cystourethroscopy with irrigation and evacuation of multiple obstructing clotsClot evacuation
52005Cystourethroscopy with ureteral catheterizationUreteral cath bilateral or unilateral
52007Cystourethroscopy with ureteral catheterization with brush biopsyBiopsy via ureter
52010Cystourethroscopy with ejaculatory duct catheterizationEjaculatory duct
52204Cystourethroscopy with biopsyBladder biopsy via scope
52214Cystourethroscopy with fulgurationAblation of lesion
52224Cystourethroscopy with fulguration of trigoneTrigone-specific
52234Cystourethroscopy with fulguration and/or resection of small bladder tumor, less than 0.5 cmTURBT small
52235Cystourethroscopy with fulguration and/or resection of medium bladder tumor, 0.5-2.0 cmTURBT medium
52240Cystourethroscopy with fulguration and/or resection of large bladder tumorTURBT large
52250Cystourethroscopy with insertion of radioactive substanceBrachytherapy implant
52260Cystourethroscopy with dilation of bladder for interstitial cystitis under anesthesiaIC dilation
52265Cystourethroscopy with dilationRoutine dilation
52270Cystourethroscopy with internal urethrotomy, femaleFemale urethrotomy
52275Cystourethroscopy with internal urethrotomy, maleMale urethrotomy
52276Cystourethroscopy with direct vision internal urethrotomyDVIU
52277Cystourethroscopy with resection of external sphincterSphincterotomy
52281Cystourethroscopy with calibration and/or dilation of urethral strictureStricture dilation
52282Cystourethroscopy with insertion of permanent urethral stentUrethral stent
52283Cystourethroscopy with steroid injection into strictureStricture injection
52285Cystourethroscopy with treatment of urethral syndrome in femaleFemale urethral syndrome
52287Cystourethroscopy with injection(s) for chemodenervation of the bladderBotox bladder
52290Cystourethroscopy with ureteral meatotomy, unilateral or bilateralMeatotomy
52300Cystourethroscopy with resection or fulguration of orthotopic ureterocele, unilateral or bilateralUreterocele resection
52301Cystourethroscopy with resection or fulguration of ectopic ureterocele, unilateral or bilateralEctopic ureterocele
52305Cystourethroscopy with incision or resection of orifice of bladder diverticulumDiverticulum
52310Cystourethroscopy with removal of foreign body, calculus, or ureteral stent from urethra or bladder, simpleForeign body/stent removal
52315Cystourethroscopy with removal of foreign body, calculus, or ureteral stent, complicatedComplex removal
52317Litholapaxy; crushing or fragmentation of calculus by any means in bladder, less than 2.5 cmBladder stone
52318Litholapaxy; complicated or large, greater than 2.5 cmLarge bladder stone
52320Cystourethroscopy with ureteroscopy, with removal of ureteral calculusUreteroscopy URS stone
52325Cystourethroscopy with ureteroscopy, with lithotripsyURS with laser/fragmentation
52327Cystourethroscopy with ureteroscopy, with subureteric injection of implant materialDeflux injection
52330Cystourethroscopy with ureteroscopy, with removal of foreign body or calculus from ureter, complicatedComplex URS
52332Cystourethroscopy with insertion of indwelling ureteral stentStent placement β€” JJ stent
52334Cystourethroscopy with creation of ureterovesical fistulaFistula creation
52341Cystourethroscopy with treatment of ureteral stricture, dilationUreteral stricture dilation
52342Cystourethroscopy with treatment of ureteral stricture, dilation, complicatedComplex stricture dilation
52343Cystourethroscopy with treatment of renal pelvic stricture, dilationRenal pelvis stricture
52344Cystourethroscopy with treatment of ureteral stricture, endoscopic incisionUreteral stricture incision
52345Cystourethroscopy with treatment of ureteral stricture, incision, complicatedComplex ureteral stricture
52346Cystourethroscopy with treatment of renal pelvic stricture, incisionRenal pelvis stricture
52351Cystourethroscopy with ureteroscopy and/or pyeloscopy, diagnosticDiagnostic upper tract
52352Cystourethroscopy with ureteroscopy and/or pyeloscopy, removal of calculusURS stone removal
52353Cystourethroscopy with ureteroscopy and/or pyeloscopy, lithotripsyURS lithotripsy
52354Cystourethroscopy with ureteroscopy and/or pyeloscopy, with biopsyUpper tract biopsy
52355Cystourethroscopy with ureteroscopy and/or pyeloscopy, with resection of tumorUpper tract tumor resection
52356Cystourethroscopy with ureteroscopy and/or pyeloscopy with lithotripsy including insertion of indwelling stentURS with laser + stent

TURP Family

CPTDescription
52601Transurethral electrosurgical resection of prostate, completeTURP
52630Transurethral resection of prostate, residual or regrowth tissueRe-TURP
52640Transurethral resection of postoperative bladder neck contractureBNC resection
52647Laser coagulation of prostate, non-contactVLAP/coagulation laser
52648Laser vaporization of prostate, contactPVP/KTP laser
52649Laser enucleation of prostate, without morcellationHoLEP without morcellation

Prostate β€” Excision and Surgery

CPTDescriptionNotes
55700Prostate biopsy, needle or punch, single or multipleSystematic TRUS biopsy
55705Prostate biopsy, incisional (usually transperineal)Transperineal biopsy
55706Prostate biopsy, transperineal, image-guided, stereotactic templateSaturation/template biopsy
55801Prostatectomy, perineal subtotalOpen perineal
55810Prostatectomy, perineal radicalOpen radical perineal prostatectomy
55812Prostatectomy, perineal radical with lymphadenectomyOpen radical + LND
55815Prostatectomy, perineal radical with bilateral pelvic lymphadenectomyFull radical perineal
55821Prostatectomy, suprapubic, subtotalOpen suprapubic
55831Prostatectomy, retropubic, subtotalOpen retropubic subtotal
55840Prostatectomy, retropubic radicalOpen radical retropubic prostatectomy (RRP)
55842Prostatectomy, retropubic radical with limited pelvic lymphadenectomyRRP + limited LND
55845Prostatectomy, retropubic radical with bilateral pelvic lymphadenectomyFull radical RRP
55860Exposure of prostate, any approach, for insertion of radioactive substanceBrachytherapy exposure
55862Same, with lymph node biopsyWith node sampling
55865Same, with bilateral pelvic lymphadenectomyWith LND
55866Laparoscopic or robotic-assisted laparoscopic prostatectomy, retropubic radical, with or without nerve sparingRARP/LRP β€” robotic prostatectomy

Adrenal Gland

CPTDescriptionNotes
60540Adrenalectomy, partial or complete, or exploration of adrenal gland with or without biopsy; transabdominal, lumbar or dorsalOpen adrenalectomy
60545Same, with excision of adjacent retroperitoneal tumorOpen with adjacent tumor
60650Laparoscopic adrenalectomy, partial or complete, or exploration of adrenal gland with or without biopsy, transabdominal, lumbar or dorsalLaparoscopic adrenalectomy

Extracorporeal Shock Wave Lithotripsy (ESWL)

CPTDescription
50590lithotripsy, extracorporeal shock waveESWL β€” kidney or ureter stones

Urinary Incontinence and Pelvic Floor

CPTDescription
51845Abdomino-vaginal vesical neck suspensionBurch colposuspension
51990Laparoscopic urethral suspensionLaparoscopic Burch
51992Laparoscopic sling operation for stress incontinenceLaparoscopic sling
57220Plastic operation on urethral sphincter, femaleOpen sphincteroplasty
57230Plastic repair of urethroceleUrethrocele repair
53431Urethroplasty with tubularization of posterior urethra and/or lower bladder for incontinenceComplex repair
53440Sling operation for correction of male urinary incontinenceMale sling
53442Removal or revision of sling for male urinary incontinenceMale sling revision
53444Insertion of tandem cuff urinary incontinence deviceMale sling β€” tandem cuff
53445Insertion of inflatable urethral/bladder neck sphincterArtificial urinary sphincter (AUS)
53446Removal of inflatable urethral/bladder neck sphincterAUS removal
53447Removal and replacement of inflatable urethral sphincterAUS exchange
53448Removal and replacement of inflatable urethral sphincter, including pump, reservoir, cuffComplete AUS exchange
53449Repair of inflatable urethral/bladder neck sphincterAUS repair
53860Transurethral radiofrequency micro-remodeling of female bladder neck and proximal urethraRenessa procedure

Penile Procedures

CPTDescription
54001Slitting of prepuce, dorsal or lateral, simpleDorsal slit
54150Circumcision, using clamp or other device with regional dorsal penile or ring blockCircumcision with block
54160Circumcision, surgical excision, neonateNeonatal circumcision
54161Circumcision, surgical excision, other than neonatalAdult circumcision
54400Insertion of penile prosthesis; non-inflatableMalleable penile implant
54401Insertion of penile prosthesis; inflatable self-containedSelf-contained inflatable
54405Insertion of multi-component inflatable penile prosthesisIPP β€” 3-piece
54406Removal of multi-component inflatable penile prosthesisIPP removal
54408Repair of component(s) of multi-component inflatable penile prosthesisIPP component repair
54410Removal and replacement of non-inflatable penile prosthesisMalleable exchange
54415Removal and replacement of inflatable penile prosthesis, non-inflatableExchange
54416Removal and replacement of multi-component inflatable penile prosthesisComplete IPP exchange
54417Removal and replacement of non-inflatable or inflatable self-contained penile prosthesisExchange
54520Orchiectomy, simpleSimple testicle removal
54522Orchiectomy, partialPartial orchiectomy
54530Orchiectomy, radical, for tumorRadical orchiectomy
54535Orchiectomy, radical, with abdominal explorationWith abdominal LND

Global Period Quick Reference

Global PeriodDescriptionExamples
000Same-day minor procedureCystoscopy, straight cath
01010-day globalTURBT small, some minor endoscopic
09090-day globalMajor open and laparoscopic surgeries
MMMMaternityNot applicable to urology
XXXNo global periodDiagnostic procedures, pathology
YYYGlobal N/A (facility determines)Some facility-based services
ZZZAdd-on codeFollows primary code global

Assistant at Surgery β€” Major Urology Procedures

CPTProcedureAssistant Payable
50230Open radical nephrectomy with LND/thrombectomyYes
50240Partial nephrectomy, openYes β€” complex cases
51575Cystectomy with bilateral pelvic LNDYes
51595Radical cystectomy with ureteroenteric diversion + LNDYes
55845Radical prostatectomy retropubic with bilateral LNDYes
55866Robotic/laparoscopic radical prostatectomyYes
50546Laparoscopic radical nephrectomy with LNDYes

Always verify the specific CPT MPFS assistant-at-surgery indicator β€” status may change with annual MPFS updates.


Common ICD-10-CM Diagnoses Driving Urology Procedures

ICD-10-CMDescriptionCommon Procedure
C64.1Malignant neoplasm of right kidney50230, 50546, 50240
C64.2Malignant neoplasm of left kidney50230, 50546, 50240
C65.1Malignant neoplasm of right renal pelvis50234, 50548
C65.2Malignant neoplasm of left renal pelvis50234, 50548
C67.xMalignant neoplasm of bladder51570-51597, 52240
C61Malignant neoplasm of prostate55840-55866
C62.xMalignant neoplasm of testis54530
N20.0Calculus of kidney50080, 50081, 50590
N20.1Calculus of ureter52352, 52353, 52356
N20.2Calculus of kidney with ureter50080, 52356
N40.1BPH with LUTS52601, 52648, 52649
N39.0UTI unspecified52000, 52332
N13.5Crossing vessel and stricture of ureter50400, 50544
N32.81Overactive bladder52287 (Botox), 51729 (urodynamics)
N39.3Stress incontinence, female51992, 57220
N99.110Post-procedural urethral stricture, male52276, 52281
Q61.xPolycystic kidney disease50220-50230 (rare)

Modifier Quick Reference for Urology

ModifierUse Case
-22Significantly increased complexity β€” document in operative note
-50Bilateral procedure β€” bilateral ESWL, bilateral stents, bilateral orchiectomy
-51Multiple procedures β€” secondary procedure on same day
-52Reduced services β€” incomplete procedure
-53Discontinued procedure β€” started, could not complete
-54Surgical care only β€” surgeon performs surgery, others manage follow-up
-55Postoperative management only β€” co-managing surgeon handles follow-up
-58Staged procedure β€” planned second procedure within global period
-59Distinct procedural service β€” used to unbundle separately payable procedures
-62Two surgeons β€” complex urologic procedures requiring co-primary surgeons
-78Unplanned return to OR β€” complication within global period
-79Unrelated procedure within global period
-80MD surgical assistant
-82Assistant when qualified resident unavailable
-ASPA/NP/CNS first assist
-RT/-LTRight/left laterality β€” required for unilateral procedures
-XUUnusual non-overlapping service β€” alternative to 59 for distinct services

Suggested Obsidian Linkouts