DEFINITION of -esis

Forms abstract nouns: condition (of), state (of); The suffix -esis is a Greek-derived noun-forming element that appears extensively throughout medical terminology to designate conditions, processes, states, or actions—particularly those of a pathological nature. It transforms verb roots into nouns that describe either normal physiological processes or abnormal disease states. In medical usage, -esis typically indicates an ongoing condition or process rather than a single discrete event, and it often describes processes that are either involuntary or occurring at a systemic level. The suffix is particularly common in describing bodily functions, disease processes, surgical procedures, and diagnostic findings. Words ending in -esis frequently describe conditions that are observable, measurable, or clinically significant, making this suffix fundamental to diagnostic and procedural medical terminology. The suffix can indicate both benign physiological processes (like diuresis) and pathological states (like enuresis), with context determining the clinical significance.


ETYMOLOGY of -esis

greek - Origin: Ancient Greek

  • Root: From Greek suffix -esis (-εσις), derived from verb endings
  • Linguistic Function: Noun-forming suffix attached to Greek verb stems to create abstract nouns denoting action, process, or resulting state
  • Grammatical Category: Creates feminine nouns in Greek (first declension)
  • Historical Usage: Used in classical Greek medical texts (Hippocratic Corpus, Galen) and maintained through Byzantine medical tradition into Arabic and Latin medical literature, then into modern medical terminology
  • Related Greek Forms: Often appears with related suffixes like -osis (condition/disease) and -iasis (abnormal condition/infestation)
  • -sis: Shortened form when attached to stems ending in vowels (e.g., “analysis” from ana- + -lysis, “crisis”)
  • -iasis: Extended form typically indicating infestation, presence of, or pathological condition (e.g., “lithiasis,” “psoriasis”)
  • -osis: Related suffix indicating condition, disease, or abnormal increase (e.g., “necrosis,” “stenosis”)

RELATED TERMS to -esis

| -esis | condition (of) | state (of) | - | |:----------:|:--------------:|:----------:|:--------------:| | -a | Yes | Yes | - | | -ema | Yes | Yes | - | | -ia | Yes | Yes | - | | -ism | Yes | Yes | quality of | | -ismus | Yes | Yes | muscular spasm | | -sis | Yes | Yes | - | | -ty | Yes | Yes | - | | -y | Yes | Yes | - |

Medical Terms Using -esis (Organized by Clinical Category):

Urological Terms (Relevant to your specialty):

  1. Enuresis - Involuntary urination, especially bedwetting (from Greek en- = in + ouron = urine + -esis)
  1. Diuresis - Increased or excessive production of urine (from Greek dia- = through + ouron = urine + -esis)
  • Related: osmotic diuresis, water diuresis
  1. Uresis - The act of urination (from Greek ouron = urine + -esis)
    • Less commonly used standalone term
  2. Lithogenesis - Formation of calculi or stones (from Greek lithos = stone + genesis = creation)
  • Relevant in urolithiasis cases Ophthalmological Terms (Relevant to your specialty):

  1. Chromesthesia - A form of synesthesia where sounds produce color sensations
  1. Photesthesia - Sensitivity to light (from Greek photos = light + aisthesis = sensation)
  • Variant spelling

Otolaryngological Terms (Relevant to your specialty):

  1. Rhinogenesis - Development or formation of the nose (from Greek rhis/rhinos = nose + genesis = formation)
  2. Phonesis - The utterance of sound (from Greek phone = voice/sound + -esis)
  • Related to phonation disorders

Compound Terms with -esis:

  1. Antiemesis - Prevention of vomiting
  • Related term: antiemetic (adjective/noun form)
  1. [[Hematemesis]] - Vomiting of blood (from Greek haima = blood + emein = to vomit + -esis)
  • Important diagnostic sign
  1. Melena vs Hematochezia - Note: while these don’t use -esis, they’re related GI bleeding terms often coded alongside hematemesis


Med roots dictionary Appendix A Prefixes Appendix B Combining Forms Appendix C Suffixes Appendix D Suffix forms