Make; -fect is a bound Latin root meaning “to make, to do, or to act upon.” It does not stand alone as a word; it only appears when a prefix is attached (e.g., in-fect, de-fect, ef-fect). In medical terminology it conveys the idea of something being acted upon, produced, or caused — most critically seen in infect (to “make inroads into” a host) and defect (something “made” incompletely or wrongly).
infectin- (into) + fect (make) To introduce pathogenic organisms into a host
infectionin- + fect + -ion (state of) The state of being invaded by a pathogen
infectiousin- + fect + -ious Capable of transmitting disease
infectivein- + fect + -ive Having the quality of causing infection
defectde- (down/away) + fect A structural or functional imperfection; e.g., septal defect
defectivede- + fect + -ive Functioning below normal standard
effectex- (out) + fect The result produced by an action; the “made” outcome
effectiveex- + fect + -ive Able to produce the desired result
affectad- (toward) + fect To act upon or influence (a tissue, organ, emotion)
transfectiontrans- (across) + fect + -ion Deliberate introduction of nucleic acids into a eukaryotic cell
reinfectre- (again) + infect To infect again after recovery
disaffectdis- + af- + fect To make unfavorable; loss of function allegiance
perfectper- (thoroughly) + fect “Thoroughly made”; complete
prefectprae- (before) + fect One “made” to rule before others
refectionre- (again) + fect + -ion Restoration; refreshment — root of refectory
Related Terms & See Also
fac- — unshifted form of same root (facile, facade)
fact- — past participial standalone form (factor, artifact)