-sclerosis

DEFINITION of -sclerosis

forms nouns: scler--osis - hardening (of tissues) of; The medical suffix -sclerosis refers to the abnormal hardening of a body tissue or organ. In clinical practice, this often involves the replacement of normal functional tissue with fibrous connective tissue, leading to a loss of elasticity.

---

ETYMOLOGY of -sclerosis

greek The term originates from the Ancient Greek word sklērōsis (σκλήρωσις), meaning “hardening”. This is derived from the root sklēros (σκληρός), which translates to “hard”. It entered English via Medieval Latin in the late 14th century, initially describing hard tumors or morbid tissue hardening.

---

RELATED TERMS to -sclerosis

Related Terms and Concepts

• -malacia: The opposite of sclerosis, this suffix denotes the abnormal softening of tissues (e.g., osteomalacia).
• -osis: Often combined with the root scler- (as in sclerosis), this suffix generally indicates an abnormal condition or disease state.
• Fibrosis: While similar, fibrosis specifically refers to the scarring and development of excess fibrous connective tissue.

---

DERIVATIONS of -sclerosis

TABLE definition AS Definition 
WHERE length(filter(roots, (word) => econtains([[]].roots, word))) > 0 AND file.name != [[]].file.name
SORT file.name ASC

---

Query

TABLE definition AS Definition
FROM #medroot
WHERE length(filter(definition, (word) => econtains([[]].definition, word))) > 0 AND file.name != [[]].file.name

Med roots dictionary