An autoimmune disease arises from the adaptive immune system’s anomalous reaction, mistakenly targeting self-tissues as foreign invaders, affecting over 80 conditions and nearly any body part, with symptoms including fatigue, joint pain, and rashes that fluctuate in flares and remissions
greek The term “autoimmune,” coined around 1952, combines Greek “auto-” (self, from αὐτός/autós) and English “immune” (from Latin immunis, exempt from public service or obligation).
RELATED TERMS
Autoantibody: Antibody targeting self-antigens.
Autoimmunity: The state of immune response against self
Examples of diseases: Type 1 diabetes (pancreas attack), multiple sclerosis (myelin sheath), systemic lupus erythematosus (multi-organ).