DEFINITION of embolism

An embolism occurs when an embolus — a solid, liquid, or gaseous mass — travels through the circulatory system and lodges in a vessel too narrow to allow its passage, obstructing blood flow. The embolus can originate from a thrombus (blood clot), fat (from long bone fractures or liposuction), air/gas (from IV lines, surgery, or barotrauma), amniotic fluid (obstetric complication), septic material (infected vegetation from endocarditis), tumor fragments, cholesterol crystals, or orthopedic bone cement. The clinical consequences depend on where the embolus lodges: the pulmonary circulation (pulmonary embolism/PE) causes hypoxia and right heart strain; the systemic arteries (arterial embolism) causes acute ischemia to organs or extremities; the cerebral circulation causes stroke or TIA; the venous system (deep vein thrombosis/DVT) represents the thrombus source most commonly leading to PE. Embolism is distinct from thrombosis (in-situ clot formation), though both may coexist and ICD-10 often codes them together.


ETYMOLOGY of embolism

greek

ComponentOriginMeaning
embol-Greek embolos (ἔμβολος), from emballeinA plug, wedge, or stopper; “to throw in” or “to insert
-ismGreek -ismosA condition, process, or pathological state

Literally: “a condition of plugging” — from the image of a wedge or stopper being thrown into a vessel and blocking it. The term was coined by Rudolf Virchow in the 1840s, the same pathologist who described Virchow’s Triad (the three factors predisposing to thromboembolism).


🔀 ALIASES / ALTERNATE TERMS

By Type of Embolus:

  • Thromboembolism — embolus arising from a blood clot (most common type)
  • Pulmonary embolism (PE) — thrombus lodged in pulmonary artery
  • Deep vein thrombosis (DVT) — the most common source of PE
  • Arterial embolism — embolus in a systemic artery
  • Fat embolism / Fat embolism syndrome (FES) — fat globules, often post-fracture
  • Air embolism / Gas embolism — air in venous or arterial system
  • Septic embolism — infected thrombus, often from endocarditis
  • Cholesterol embolism / Atheroembolism — cholesterol crystals from plaque rupture
  • Tumor embolism — malignant cells in circulation
  • Amniotic fluid embolism (AFE) — obstetric emergency
  • Cement embolism — acrylic bone cement (orthopedic procedures)
  • Paradoxical embolism — venous embolus crossing to arterial circulation via PFO/ASD

By Location:

  • Saddle embolus — large embolus straddling a bifurcation (e.g., pulmonary artery bifurcation or aortic bifurcation)
  • Massive PE — causing hemodynamic instability/shock
  • Submassive PE — with right heart strain but without shock
  • Subsegmental PE — in the smallest pulmonary arterial branches
  • Chronic thromboembolic pulmonary hypertension (CTEPH) — long-term PE complication

🔗 RELATED TERMS

  • Thrombus — the in-situ clot that becomes an embolus when it breaks off
  • Virchow’s Triad — hypercoagulability, venous stasis, endothelial injury (risk factors for thromboembolism)
  • DVT (Deep Vein Thrombosis) — most common PE source; category I82
  • Cor pulmonale — right heart failure from pulmonary hypertension due to PE
  • Infarction — tissue death from embolic arterial occlusion
  • Anticoagulation — primary treatment (heparin, warfarin, DOACs)
  • Thrombolysis (tPA) — for massive/life-threatening PE
  • Thrombectomy / Embolectomy — surgical or catheter-based removal
  • IVC filter — inferior vena cava filter to catch emboli
  • V/Q scan — ventilation-perfusion scan for PE diagnosis
  • CT Pulmonary Angiography (CTPA) — gold standard PE imaging
  • D-dimer — screening lab for thromboembolism
  • Wells score / PERC rule — clinical prediction rules for PE probability

CODING CORNER


### 🏥 ICD-10-CM CODES

Pulmonary Embolism (Category I26)

CodeDescription
I26.01Septic pulmonary embolism with acute cor pulmonale
I26.02Saddle embolus of pulmonary artery with acute cor pulmonale
I26.03Cement embolism of pulmonary artery with acute cor pulmonale
I26.04Fat embolism of pulmonary artery with acute cor pulmonale
I26.09Other pulmonary embolism with acute cor pulmonale
I26.90Septic pulmonary embolism without acute cor pulmonale
I26.92Saddle embolus of pulmonary artery without acute cor pulmonale
I26.93Single subsegmental thrombotic pulmonary embolism without acute cor pulmonale
I26.94Multiple subsegmental thrombotic pulmonary emboli without acute cor pulmonale
I26.95Cement embolism of pulmonary artery without acute cor pulmonale
I26.96Fat embolism of pulmonary artery without acute cor pulmonale
I26.99Other pulmonary embolism without acute cor pulmonale
I27.82Chronic pulmonary embolism

Arterial Embolism & Thrombosis (Category I74)

CodeDescription
I74.01Saddle embolus of abdominal aorta
I74.09Other embolism and thrombosis of abdominal aorta
I74.10Embolism and thrombosis of unspecified parts of aorta
I74.11Embolism and thrombosis of thoracic aorta
I74.19Embolism and thrombosis of other parts of aorta
I74.2Embolism and thrombosis of arteries of the upper extremities
I74.3Embolism and thrombosis of arteries of the lower extremities
I74.4Embolism and thrombosis of arteries of extremities, unspecified
I74.5Embolism and thrombosis of iliac artery
I74.8Embolism and thrombosis of other arteries
I74.9Embolism and thrombosis of unspecified artery
I76Septic arterial embolism

Venous Embolism & Thrombosis — DVT (Category I82, selected)

CodeDescription
I82.411Acute embolism and thrombosis of right femoral vein
I82.412Acute embolism and thrombosis of left femoral vein
I82.421Acute embolism and thrombosis of right iliac vein
I82.422Acute embolism and thrombosis of left iliac vein
I82.431Acute embolism and thrombosis of right popliteal vein
I82.432Acute embolism and thrombosis of left popliteal vein
I82.441Acute embolism and thrombosis of right tibial vein
I82.442Acute embolism and thrombosis of left tibial vein
I82.451Acute embolism and thrombosis of right peroneal vein
I82.452Acute embolism and thrombosis of left peroneal vein
I82.3Embolism and thrombosis of renal vein
I82.B11Acute embolism and thrombosis of right subclavian vein
I82.B12Acute embolism and thrombosis of left subclavian vein
I82.A11Acute embolism and thrombosis of right axillary vein
I82.A12Acute embolism and thrombosis of left axillary vein
I82.90Acute embolism and thrombosis of unspecified vein
I82.91Chronic embolism and thrombosis of unspecified vein

Cerebral Embolism (causing infarction)

CodeDescription
I63.131Cerebral infarction due to embolism of right carotid artery
I63.132Cerebral infarction due to embolism of left carotid artery
I63.111Cerebral infarction due to embolism of right vertebral artery
I63.112Cerebral infarction due to embolism of left vertebral artery
I63.19Cerebral infarction due to embolism of other precerebral artery

Traumatic & Special Types (Category T79)

CodeDescription
T79.0XXAAir embolism (traumatic), initial encounter
T79.0XXDAir embolism (traumatic), subsequent encounter
T79.0XXSAir embolism (traumatic), sequela
T79.1XXAFat embolism (traumatic), initial encounter
T79.1XXDFat embolism (traumatic), subsequent encounter
T79.1XXSFat embolism (traumatic), sequela

History / Status

CodeDescription
Z86.711Personal history of pulmonary embolism
Z86.718Personal history of other venous thrombosis and embolism

Diagnostic Imaging

CPT CodeDescription
71275CT angiography, thorax (CTPA — primary PE imaging)
78582V/Q scan (pulmonary perfusion imaging with ventilation)
78580Pulmonary perfusion imaging only
93306Echocardiography with Doppler (assess RV strain in PE)
76706Ultrasound, abdominal aorta, screening
93971Duplex scan, extremity veins, unilateral (DVT workup)
93970Duplex scan, extremity veins, bilateral

Interventional / Surgical

CPT CodeDescription
37187Percutaneous transluminal mechanical thrombectomy, venous
37188Percutaneous transluminal mechanical thrombectomy, venous (repeat)
37212Thrombolytic therapy, venous (infusion)
37213Thrombolytic therapy, venous (continued infusion)
37184Percutaneous transluminal mechanical thrombectomy, arterial
37185Arterial thrombectomy (second vessel)
33973Balloon pump insertion (for massive PE with cardiogenic shock)
37191Insertion of IVC filter, endovascular
37192Repositioning of IVC filter
37193Retrieval of IVC filter
33999Surgical pulmonary embolectomy (unlisted cardiac procedure — used with operative report)
34201Embolectomy/thrombectomy, femoral/popliteal artery
34101Embolectomy/thrombectomy, axillary, brachial, innominate, subclavian artery
34151Embolectomy/thrombectomy, renal, celiac, mesenteric, aortoiliac artery

⚠️ Coding Note: Pulmonary embolism codes under I26.xx are MCC (Major Complication/Comorbidity) when associated with acute cor pulmonale and CC without it — making specificity critical for MS-DRG weight. Always document and code whether cor pulmonale is present. The saddle embolus codes (I26.02, I26.92, I74.01) are distinct and should be used when specifically documented — they reflect higher severity. For DVT + PE occurring together, code both the I26.xx and the appropriate I82.xx — they are not mutually exclusive. Chronic PE (I27.82) is separate from acute PE and represents organized, unresolved thrombus causing chronic pulmonary hypertension (CTEPH). For fat embolism post-fracture or orthopedic surgery, T79.1XXA carries the 7th character and must be sequenced appropriately with the causative condition.



Med roots Appendix A Prefixes Appendix B Combining Forms Appendix C Suffixes Appendix D Suffix forms