Glossectomy involves the partial or total resection of the tongue, determined by the size, location, and extent of the tumor or lesion, often with margins of healthy tissue to ensure complete removal of malignant cells. Partial glossectomy removes a portion of the tongue, hemi-glossectomy removes half (typically one lateral side), subtotal removes most but not all, and total glossectomy removes the entire tongue, often requiring reconstruction with grafts (e.g., from thigh, forearm, or abdomen) and possibly laryngectomy to prevent aspiration. It is typically done under general anesthesia by head and neck surgeons, with postoperative challenges including speech impairment (dysarthria), swallowing difficulties (Dysphagia), taste changes, and need for speech/swallow therapy. Reconstruction uses pedicled or free flaps (e.g., radial forearm free flap, anterolateral thigh flap) to restore function and prevent complications like fistula or airway obstruction.