DEFINITION of nephrectomy

A nephrectomy is a surgical procedure involving the partial or complete removal of one kidney. It may be performed to treat malignancy, severe trauma, nonfunctioning kidneys, congenital abnormalities, or to procure a kidney for transplantation. From a medical‑coding perspective, nephrectomy documentation must clarify: Extent (partial vs. total) Approach (open, laparoscopic, robotic) Indication (tumor, obstruction, infection, donation) Laterality (right, left) Additional procedures (lymphadenectomy, adrenalectomy, ureterectomy) These distinctions directly affect CPT and ICD‑10‑PCS code selection. Nephrectomy is the surgical removal of a kidney, performed to treat kidney cancer, severe kidney damage, non-functioning kidneys, or to harvest a healthy kidney from a donor for transplantation. The term derives from the Greek nephros (kidney) and -ektomia (a cutting out), dating to 1880.


ETYMOLOGY of nephrectomy

greek - The word is composed of two Greek roots:

nephr-/nephro-: From Greek nephros meaning “kidney,” which traces back to Proto-Indo-European negwhro- (kidney)

-ectomy: From Greek -ektomia meaning “a cutting out of,” derived from ektemnein (“to cut out”), combining ek (“out”) + temnein (“to cut”) Nephr‑ → Greek nephros (νεφρός), meaning “kidney

  • ‑ectomy → Greek ektomē, meaning “cutting out” or “excision
  • Nephrectomy literally means “cutting out the kidney.”

Related Terms

TermMeaningCoding Relevance
nephrotomyIncision into the kidneyNot removal; used for stone extraction or exploration.
NephrolithiasisKidney stonesMay lead to nephrectomy if kidney is nonfunctional.
NephropexySurgical fixation of a kidneyOpposite of removal; kidney is preserved.
NephrolysisFreeing the kidney from adhesionsNo removal; often done during complex renal surgery.
ureterectomyRemoval of the ureterSometimes performed with radical nephrectomy.
adrenalectomyRemoval of adrenal glandMay be bundled or separately coded depending on documentation.
nephroureterectomyRemoval of kidney and ureterDistinct CPT/PCS coding.

Common Medical Terms Using the Root

  • Radical nephrectomy - Removal of the entire kidney plus surrounding tissue, possibly adrenal gland and lymph nodes

  • Partial nephrectomy - Removal of only the diseased portion of the kidney

  • Simple nephrectomy - Removal of the kidney without extensive surrounding tissue

  • Laparoscopic nephrectomy - Minimally invasive approach

  • Robotic‑assisted nephrectomy - Robotic surgical technique


Common Clinical Indications

  • Renal cell carcinoma

  • Severe hydronephrosis with loss of function

  • Polycystic kidney disease (nonfunctioning kidney)

  • Trauma

  • Chronic infection

  • Living kidney donation

Types of Nephrectomy (from Perplexity AI)

There are two main types for treating diseased kidneys

  • Partial nephrectomy (nephron-sparing surgery): Removes only the diseased or injured portion of the kidney while preserving healthy tissue, typically for tumors under 4 cm

  • Radical nephrectomy: Removes the entire kidney along with the surrounding fatty tissue, the ureter section, adrenal gland, and sometimes regional lymph nodes

  • Bilateral nephrectomy: Removal of both kidneys simultaneously​

Surgical Approaches

The procedure can be performed through

  • Open surgery: Through a side or midline incision in the abdomen

  • Laparoscopic surgery: Using 3-4 small incisions (5-10 mm) with instruments and a camera

  • Single-port laparoscopy: Advanced technique through one incision in the navel


Documentation Clues for Coders

Look for phrases such as:

  • “Kidney removed”

  • “Radical excision”

  • “Partial resection of renal mass”

  • “Gerota’s fascia removed”

  • “Adrenal gland taken en bloc”

  • “Specimen sent to pathology”

  • “Lymph nodes dissected”

  • “Warm ischemia time” (common in partial nephrectomy)

These help determine extent, approach, and bundled vs. separate procedures.

Coder’s Notes

  • Partial vs. total nephrectomy changes CPT/PCS codes significantly.

  • Radical nephrectomy may include adrenalectomy or lymphadenectomy—documentation must specify.

  • Approach matters: open, laparoscopic, robotic, or converted.

  • Laterality is essential for ICD‑10‑CM and PCS.

  • For living donor nephrectomy, coding rules differ from oncologic or traumatic indications.

  • Check for concurrent procedures: ureterectomy, tumor thrombectomy, nephrolithotomy, nephropexy.



Med roots Appendix A Prefixes Appendix B Combining Forms Appendix C Suffixes Appendix D Suffix forms