A condition where the kidney’s filtration system (the glomeruli) allows large molecules like proteins—most commonly albumin—to leak from the blood into the urinary tract. While trace amounts can be normal, persistent elevated levels typically indicate Chronic Kidney Disease (CKD) or systemic issues like hypertension and diabetes. Persistent proteinuria is a hallmark of various renal conditions, including glomerulonephritis and diabetic nephropathy. In professional medical coding (ProFee), unspecified proteinuria is typically reported using ICD-10 code R80.9. In obstetric cases, it is a key component of the “EPH” triad (Edema, proteinuria, Hypertension) used to diagnose preeclampsia.