“profuse discharge,” “excessive secretion,” “a flowing, a stream” — Noun-forming compound suffix — “condition of profuse discharge or secretion of (a fluid or substance)”
The word entered English in the 1540s as diarrhea (noun), borrowed from Middle French diarrhée, from Late Latin diarrhea, from Greek διάρροια (diarroia) — literally “a flowing through” (dia- “through” + rrhea “a discharge”). The suffix form -rrhea in medical compounds appeared in the 1800s. The root rhein (“to flow”) connects -rrhea to the entire flow and discharge suffixes: diarrhea (dia- + rrhea → flowing through / profuse intestinal discharge), galactorrhea (galacto- + rrhea → profuse milk secretion), and rhinorrhea (rhino- + rrhea → profuse nasal discharge). The compound suffix-rrhea is extremely productive across all medical specialties: e.g., menorrhea, polyrrhea, sialorrhea, urinorrhea, and otorrhea.