“to,” “toward,” “near” — directional prefix (assimilates to the initial consonant of the following root: ac- before c, af- before f, ag- before g, al- before l, an- before n, ap- before p, as- before s, at- before t)
The word entered English in the 1400s as a Latin-derived prefix (prefix), borrowed from French a-, from Latin ad — literally “to, toward.” The prefix ad- (“toward”) connects ad- to the entire directional prefixes: adduct (ad- + ducere → to lead toward), adhesion (ad- + haerere → to stick to), and adrenal (ad- + renalis → toward the kidney). The directional prefixad- is one of the most productive prefixes in medical terminology: e.g., adduction, adjuvant, afferent, append, and attrition.