🧬 ICD-10 CM H40.61X4 β€” Glaucoma Secondary to Drugs, Right Eye, Indeterminate Stage

Billable Code Confirmed β€” 7 Characters Complete

# ICD-10 CM H40.61X4 is a valid, billable 7-character ICD-10-CM code for FY2025. Structure: H40 (glaucoma) + .6 (secondary to drugs) + 1 (right eye) + X (structural placeholder) + 4 (indeterminate stage). Complete and current.

Non-Billable Parent Codes β€” Do Not Submit

  • ❌ H40.61 β€” 5-character header β€” non-billable
  • ❌ H40.6 β€” 4-character header β€” non-billable

🚨 MANDATORY ADDITIONAL CODE β€” T-Code Required

Same instruction as H40.61X1-H40.61X3: β€œUse additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).” T38.0X5D required at every ongoing monitoring visit. T38.0X5A at first encounter documenting indeterminate stage. Never submit H40.61X4 alone.

Cross-Reference

For full pathophysiology, T-code mechanics, steroid background, and CPT templates β†’ see H40.61X1. This note focuses entirely on the indeterminate stage β€” what it means, when it applies, and how it differs from unspecified.


πŸ” Code Description

H40.61X4 classifies glaucoma secondary to drug therapy, right eye, at the indeterminate stage β€” a stage designation assigned when the diagnosis of glaucoma is clinically established but the severity cannot be determined because visual field testing has not been performed, could not be completed, or produced unreliable/uninterpretable results. The glaucoma is real β€” confirmed by optic nerve examination and/or RNFL OCT findings consistent with glaucomatous damage. The stage is simply beyond the reach of current testing.

This is a legitimate, clinically valid stage β€” not a coding failure or documentation gap. The physician’s documented reason for inability to stage is what separates H40.61X4 from H40.61X0 (stage unspecified). When a cataract clouds the view, when a patient cannot cooperate with the visual field machine, or when glaucoma is newly diagnosed and testing is pending β€” indeterminate is the correct and honest answer.


πŸ”‘ The Single Most Important Concept β€” Indeterminate β‰  Unspecified

This distinction is the entire clinical and coding value of H40.61X4, and it is tested on the CIC/COC/CPC exams.

4 vs. 0 β€” Know the Difference Cold

7th CharacterCodeMeaningWhen to UseCDI Action
4H40.61X4Glaucoma confirmed β€” stage CANNOT be determined β€” clinical barrier existsMedia opacity, unreliable VF, VF not yet performed, patient incapableβœ… Use β€” document the reason
0H40.61X0Glaucoma confirmed β€” stage simply NOT documentedDocumentation gap β€” physician didn’t record stage⚠️ Last resort β€” CDI query first

Think of It This Way

Indeterminate (4) = β€œI looked, I tried, I can’t tell because of [documented reason]” Unspecified (0) = β€œNobody wrote it down”

One is a clinical answer. The other is a documentation gap. H40.61X4 is the correct code when the physician documents WHY staging is not possible.


πŸ“Š When Does Indeterminate Stage Apply?

These are the four clinical scenarios where H40.61X4 is appropriate:

Scenario Type 1 β€” Media Opacity Prevents Visual Field Testing

Media OpacityEffect on Staging
Dense cataractMost common cause β€” lens opacity reduces retinal illumination, producing an unreliable or severely depressed visual field that does not reflect true glaucomatous loss
Corneal opacity/scarReduces light transmission; distorts field testing results
Vitreous hemorrhageBlocks view; field testing unreliable until hemorrhage clears
Poorly dilating pupilMiotic pupil (Horner’s, pilocarpine use) artificially depresses visual field

The Dense Cataract + Glaucoma Dilemma β€” A Classic H40.61X4 Scenario

This is the most common real-world trigger for H40.61X4. A patient has documented glaucomatous optic nerve cupping and elevated IOP β€” confirmed glaucoma β€” but a dense posterior subcapsular cataract (coincidentally, often steroid-induced H26.13 β€” connecting directly back to H40.61X1-4!) depresses the entire visual field, making it impossible to distinguish:

  • True glaucomatous field loss from cataract-induced depression
  • The actual severity of the glaucoma

The ophthalmologist cannot reliably stage the glaucoma until the cataract is removed. Until then β†’ H40.61X4. After cataract surgery with a reliable post-op visual field β†’ re-stage to H40.61X1, H40.61X2, or H40.61X3.

This is where your steroid glaucoma (H40.61X4) and steroid cataract (H26.13) notes connect: the same steroid that caused the glaucoma often causes the PSC cataract that prevents staging it. Document both.

Scenario Type 2 β€” Unreliable Visual Field Results

A visual field is performed but the reliability indices are outside acceptable parameters, making the results uninterpretable:

Reliability IssueHVF IndicatorImpact
High fixation losses>20% fixation loss ratePatient not maintaining fixation β€” field unreliable
High false positive rate>15% false positives”Trigger happy” responses β€” artificially good-looking field
High false negative rate>33% false negativesInattentive responses β€” artificially depressed field
Short-term fluctuationExcessive SF on STATPACHighly variable responses within the test

Unreliable β‰  Failed β€” Document the Indices

When a visual field is performed but is unreliable, the physician note should document the reliability issue: β€œVisual field today unreliable β€” high fixation loss rate of 35% β€” cannot stage glaucoma based on today’s testing.” This documentation supports H40.61X4 and protects against audit challenge.

Scenario Type 3 β€” Patient Incapable of Performing Visual Field

Some patients simply cannot perform reliable perimetry regardless of how many attempts are made:

Patient LimitationClinical Context
Cognitive impairment / dementiaCannot follow instructions reliably
Severe tremor or movement disorderParkinson’s, MS β€” fixation impossible
Language barrier without interpreterCannot understand the task
Severe anxiety or claustrophobiaCannot maintain position in perimeter
Physical disability preventing positioningWheelchair/positioning challenge
Pediatric / very young patientToo young for reliable threshold perimetry

Scenario Type 4 β€” Visual Field Not Yet Performed (Newly Diagnosed)

When glaucoma is newly diagnosed at an encounter and visual field testing has been ordered but not yet completed β€” the stage is genuinely not yet determinable.

Newly Diagnosed β€” Use Indeterminate Temporarily, Not Permanently

H40.61X4 is an appropriate interim code for a newly diagnosed patient whose visual field is pending. Once the visual field is completed and reliable, re-stage to H40.61X1, H40.61X2, or H40.61X3 at the next encounter. Do not keep H40.61X4 permanently when staging becomes possible β€” update the code to reflect the confirmed stage.


🌳 The Complete H40.61X Family β€” Finished! βœ…

H40.61 Right Eye β€” Glaucoma Secondary to Drugs ❌ Non-billable  
β”‚ [T-code required at all stages]  
β”‚  
β”œβ”€β”€ H40.61X0 Unspecified ⚠️ Documentation gap β†’ CDI query  
β”‚ "Nobody wrote it down"  
β”‚  
β”œβ”€β”€ H40.61X1 Mild MD > -6 dB | Early field loss  
β”‚  
β”œβ”€β”€ H40.61X2 Moderate MD -6 to -12 dB | Significant loss, fixation intact  
β”‚  
β”œβ”€β”€ H40.61X3 Severe MD < -12 dB OR within 5Β° of fixation  
β”‚ Surgical urgency  
β”‚  
└── H40.61X4 Indeterminate ← THIS CODE βœ…  
"I tried β€” I can't tell β€” here's why"  
Media opacity | Unreliable VF | Can't perform VF | Pending VF

πŸ”¬ What the Physician Note Must Contain to Support H40.61X4

Unlike staged glaucoma codes which are supported by HVF mean deviation values, H40.61X4 is supported by documentation of the barrier to staging:

Required Documentation ElementExample Language
Glaucoma confirmed”Glaucomatous optic nerve cupping OD, confirmed on OCT RNFL”
Drug cause documented”IOP elevation and glaucoma secondary to intravitreal triamcinolone”
Staging barrier documented”Visual field testing not reliable today due to dense PSC OD β€” cannot stage”
Plan to re-stage”Will re-evaluate glaucoma stage after cataract surgery OD”

The OCT Is the Anchor at Indeterminate Stage

When visual field testing is unavailable or unreliable, OCT RNFL analysis (92133) becomes the primary structural documentation tool for H40.61X4. The OCT can confirm glaucomatous RNFL thinning β€” establishing the diagnosis β€” even when the VF cannot establish the stage. Document the OCT findings explicitly: β€œOCT RNFL OD: moderate superior and inferior thinning consistent with glaucoma β€” confirms diagnosis despite unreliable VF.”


H40.61X Family β€” Complete Right Eye Map

CodeStageCriteriaStatus
H40.61X0UnspecifiedNot documented⚠️ CDI query
H40.61X1MildMD > -6 dBβœ…
H40.61X2ModerateMD -6 to -12 dBβœ…
H40.61X3SevereMD < -12 dB or 5Β° of fixationβœ…
H40.61X4IndeterminateCannot stage β€” reason documentedβœ… This Code

Cross-Laterality

CodeDescription
H40.62X4Glaucoma secondary to drugs, left eye, indeterminate
H40.63X4Glaucoma secondary to drugs, bilateral, indeterminate

Mandatory Additional Code

CodeUse When
T38.0X5AFirst encounter documenting indeterminate stage
T38.0X5DAll ongoing visits ← Most common

Commonly Co-Coded with H40.61X4

CodeDescriptionConnection
H26.13Posterior subcapsular cataractMost common cause of indeterminate staging β€” steroid PSC preventing reliable VF
H26.9Cataract, unspecifiedWhen type not specified
H43.1xVitreous hemorrhageBlood preventing VF testing
Z79.52Long-term systemic steroid useChronic exposure documentation
H35.3221Wet AMD, right eye, active CNVIf Ozurdex caused the SIG
E11.3511T2DM with DME right eyeIf Ozurdex for DME caused SIG

πŸ› οΈ CPT Templates at Indeterminate Stage

Template A: Indeterminate Due to Dense Cataract β€” OCT Only Visit

CodeDescriptionNotes
92014Comprehensive exam, establishedFull glaucoma + cataract evaluation
92133-RTOCT optic nerve/RNFL, right eyeStructural staging substitute β€” VF unreliable
92083-RTHVF 24-2 attemptedBill even if unreliable β€” document reliability indices
H40.61X4Primary DxIndeterminate β€” PSC prevents staging
T38.0X5DRequired additional
H26.13Additional DxPosterior subcapsular cataract β€” the staging barrier

Bill the Attempted Visual Field Even If Unreliable

When a visual field is performed but produces unreliable results, 92083 is still billable β€” the test was performed and the technician’s time was used. Document the reliability indices in the report and the physician’s assessment of why the field is not interpretable. Do not avoid billing the test because it was unreliable β€” the attempt itself has clinical and billing validity.

Template B: Newly Diagnosed Indeterminate β€” Pending VF

CodeDescriptionNotes
92004 or 92014Comprehensive examNew vs. established
92133-RTOCT optic nerve/RNFLStructural diagnosis confirmation
H40.61X4Primary DxNewly diagnosed β€” VF ordered but pending
T38.0X5ARequired additionalInitial encounter β€” first diagnosis

Template C: Post-Cataract Surgery Re-Staging (Code Change Visit)

After cataract removal, reliable visual field testing becomes possible. This is the transition visit from H40.61X4 β†’ staged code.

CodeDescriptionNotes
92014Established examPost-cataract glaucoma reassessment
92083-RTHVF 24-2 SITA StandardNow reliable post-cataract β€” stages the glaucoma
92133-RTOCT RNFLStructural comparison
H40.61X1/2/3New primary DxRe-staged based on reliable post-op VF
T38.0X5DRequired additionalContinues β€” drug cause unchanged

The Post-Cataract Code Change β€” From H40.61X4 to a Staged Code

When cataract surgery restores a clear optical path and reliable visual fields become obtainable, H40.61X4 should be retired and replaced with the appropriate staged code at the first post-op visit where a reliable HVF is documented. This is not an optional update β€” the indeterminate stage was always temporary pending reliable testing, and accuracy requires updating the code once staging is possible. Document the re-staging explicitly: β€œPost-cataract VF now reliable β€” MD -7.2 dB β€” reclassifying to moderate stage.”


πŸ’Š Coding Scenarios


Scenario 1 β€” Steroid PSC Causing Indeterminate Stage (Classic)

Clinical Vignette: A 64-year-old male with steroid-induced glaucoma OD from long-term inhaled fluticasone presents for monitoring. OCT RNFL OD: moderate superior thinning. HVF 24-2 OD attempted β€” reliability indices: fixation losses 28%, false negatives 42% β€” β€œunreliable β€” cannot interpret.” Dense PSC OD also present. Physician note: β€œCannot stage glaucoma OD today β€” visual field unreliable due to dense PSC. Planning cataract surgery OD next month. Will re-stage post-operatively.”

ICD-10-CM:

  • H40.61X4 β€” Glaucoma secondary to drugs, right eye, indeterminate (confirmed glaucoma; cannot stage due to PSC/unreliable VF β€” documented reason present)
  • T38.0X5D β€” Adverse effect of glucocorticoids, subsequent encounter
  • H26.13 β€” Posterior subcapsular cataract (steroid-induced PSC β€” the barrier to staging)

Two Steroid Complications, One Patient, Same Cause

This scenario perfectly illustrates the steroid complication cascade: the same inhaled fluticasone caused both the glaucoma (H40.61X4) and the PSC cataract (H26.13) β€” and the cataract is now preventing accurate staging of the glaucoma. Both codes belong on the same claim, both pointing back to the same T38.0X5D adverse effect code. Crystal, this trifecta is a high-yield scenario for the CIC exam.


Scenario 2 β€” Newly Diagnosed, VF Pending (Indeterminate β†’ Staged Transition)

Visit 1: A 58-year-old female on chronic prednisolone for lupus presents for routine eye exam. IOP OD: 34 mmHg. Optic nerve OD: C/D ratio 0.8, rim thinning superior and inferior. OCT RNFL OD: significant superior and inferior thinning. Physician: β€œNew diagnosis of steroid-induced glaucoma OD. Visual field ordered β€” appointment scheduled for next week. Cannot stage at this time.”

Visit 1 ICD-10-CM:

  • H40.61X4 β€” Indeterminate (newly diagnosed; VF pending)
  • T38.0X5A β€” Initial encounter (first visit for this diagnosis)
  • M32.9 β€” SLE (reason prednisolone was prescribed)

Visit 2 (1 week later): HVF 24-2 OD: reliable (FL 8%, FP 3%, FN 12%). MD -9.4 dB. Pattern deviation: superior and inferior arcuate defects, not within 5Β° of fixation. Physician: β€œModerate drug-induced glaucoma OD β€” MD -9.4 dB β€” starting latanoprost.”

Visit 2 ICD-10-CM β€” Stage Updated:

  • H40.61X2 β€” Moderate stage (MD -9.4 dB = moderate; H40.61X4 retired β€” staging now possible)
  • T38.0X5D β€” Subsequent encounter (now follow-up)
  • M32.9 β€” SLE

Scenario 3 β€” Cognitively Impaired Patient, Cannot Perform VF

Clinical Vignette: An 84-year-old female with moderate dementia and known drug-induced glaucoma OD from chronic ophthalmic steroid use is brought in by her daughter. IOP OD: 26 mmHg on latanoprost + timolol. OCT RNFL OD: advanced superior and inferior thinning. Visual field attempted β€” patient cannot follow instructions β€” test aborted after 3 attempts. Physician: β€œUnable to perform reliable visual field today due to moderate dementia β€” cannot stage. OCT suggests possible severe damage. Continue current drops, add brimonidine.”

ICD-10-CM:

  • H40.61X4 β€” Indeterminate (dementia prevents reliable VF β€” cannot stage despite attempts; OCT findings suggest possible severity but HVF criteria required for staging)
  • T38.0X5D β€” Adverse effect of glucocorticoids, subsequent encounter
  • F02.80 β€” Dementia in other diseases, without behavioral disturbance (underlying condition preventing staging)

OCT Alone Does NOT Establish Stage β€” HVF Required

Even though the OCT in this scenario β€œsuggests possible severe damage,” ICD-10-CM glaucoma staging requires visual field criteria (Hodapp-Parrish-Anderson / HPA criteria based on HVF mean deviation). [web:244][web:247] OCT structural data alone β€” without a reliable HVF β€” supports the diagnosis but does not establish the stage. The physician correctly codes indeterminate (H40.61X4) rather than assuming severe based on OCT alone. When the visual field is not obtainable, the stage is indeterminate β€” period.


⚠️ Full H40.61X Family β€” Final Comparison Table

H40.61X0H40.61X1H40.61X2H40.61X3H40.61X4
StageUnspecifiedMildModerateSevereIndeterminate
MDNot documented> -6 dB-6 to -12 dB< -12 dBCannot determine
Use whenLast resort ⚠️VF reliable; early lossVF reliable; mod lossVF reliable; advancedClinical barrier to staging
T-codeT38.0X5x βœ…T38.0X5x βœ…T38.0X5x βœ…T38.0X5x βœ…T38.0X5x βœ…
CDI actionQuery stageNone neededNone neededNone neededDocument reason
OCT coverageβœ…βœ…βœ…βœ… [web:54]βœ…
Temporary?IdeallyNoNoNoOften β€” re-stage when possible

⚠️ Coding Pitfalls and Tips

Pitfall or Tip
❌Never submit H40.61X4 without T38.0X5x T-code β€” mandatory
❌Never use H40.61X4 as a permanent default β€” it is appropriate temporarily; update to a staged code when reliable VF becomes possible
❌Never use H40.61X4 interchangeably with H40.61X0 β€” indeterminate has a documented clinical reason; unspecified is a documentation gap
❌Never stage glaucoma from OCT alone β€” HVF mean deviation drives stage assignment; OCT supports the diagnosis but not the stage
❌Never skip billing 92083 because the VF was unreliable β€” the test was performed; bill it and document the unreliability
βœ…H40.61X4 = confirmed glaucoma + documented barrier to staging β€” the diagnosis is NOT in question; only the severity
βœ…Document the specific barrier β€” β€œdense PSC,” β€œunreliable VF (FL 28%),” β€œpatient unable to cooperate due to dementia,” β€œVF pending”
βœ…Plan to re-stage is good practice β€” β€œwill re-stage after cataract surgery” shows clinical intent and supports record continuity
βœ…OCT (92133) is the anchor at indeterminate stage β€” structural evidence of glaucoma when VF is unavailable
βœ…Steroid PSC + H40.61X4 is a classic trifecta β€” same drug causes glaucoma AND the cataract preventing staging; code all three
βœ…H40.61X4 confirmed on CMS LCD A56916 as covered Dx for 92133 β€” OCT billing supported at indeterminate stage
βœ…RT modifier on all unilateral right-eye CPT codes
βœ…T38.0X5A at first indeterminate encounter; T38.0X5D at all follow-up visits

πŸ“š Sources

1. CMS LCD Article A56916 β€” Scanning Computerized Ophthalmic Diagnostic Imaging (SCODI). Full H40.61X family confirmed β€” H40.61X0 through H40.61X4 listed as covered diagnoses for CPT 92133 (OCT optic nerve/RNFL). Revised December 2024. [web:54]

2. Unbound Medicine ICD-10-CM. β€œH40.61X4 β€” Glaucoma secondary to drugs, right eye [indeterminate stage].” Code confirmed. [web:242]

3. Coding Billing Solutions. β€œGlaucoma ICD-10 Codes.” Full H40.61X family structure confirmed β€” X placeholder + stage digit; H40.61X4 indeterminate confirmed in family listing. [web:199]

4. AAPC. ICD-10-CM Code H40.61 β€” Glaucoma secondary to drugs, right eye. T-code use additional code instruction confirmed. [web:207]

5. Ophthalmology Management. β€œICD-10 Comes to Glaucoma.” Indeterminate stage (7th digit β€œ4”) defined: β€œEither the doctor cannot determine the nature of the visual field loss, or the patient has not been tested yet, or the patient performed very poorly on the visual field test so the physician cannot rely on the test results to arrive at a diagnosis.” β€” Dr. Cynthia Mattox, New England Eye Center; Kevin Corcoran, CPC. [web:244]

6. Eyes on Eyecare. β€œ12 Different Glaucoma ICD-10 Codes β€” How and When to Use Them.” Staging digit 4 = indeterminate stage confirmed. [web:246]

7. Glaucoma Today / BMC Today. β€œICD-10-CM for Glaucomatologists.” Dr. Cynthia Mattox, AGS Patient Care Committee. Indeterminate stage: β€œvisual fields not performed yet, patient incapable of visual field testing, or unreliable/uninterpretable visual field testing.” [web:247]

8. See H40.61X1 for full citation list covering pathophysiology, T-code adverse effect framework, and steroid-induced glaucoma clinical background.