-cele refers to a hernia, tumor-like swelling, or abnormal herniation where an organ, fluid-filled sac, or tissue protrudes through a defect in the surrounding wall or membrane, often requiring surgical correction. It commonly describes congenital or acquired defects like meningeal herniations (e.g., spina bifida cystica) or pelvic organ prolapses, distinguishing them from solid tumors (-oma).