Episcleritis is a benign, usually idiopathic inflammatory condition affecting the episcleral tissue, which is the superficial layer overlying the white of the eye (sclera). It manifests as sectoral or diffuse injection (redness) of the eye, often accompanied by mild tenderness, irritation, and lacrimation, but notably without significant visual disturbance or pain severe enough to suggest scleritis. It occurs in two primary clinical forms: simple (diffuse) and nodular. A third variant, episcleritis periodica fugax, is a transient, recurrent form that resolves spontaneously within hours to days. While most cases are idiopathic, episcleritis can be associated with systemic conditions such as rheumatoid arthritis, inflammatory bowel disease, gout, rosacea, or — less commonly — tuberculosis. It is differentiated from the more serious scleritis by the blanching of episcleral vessels with topical phenylephrine (the “phenylephrine blanching test”), the absence of deep boring pain, and its generally benign, self-resolving course. Related / Differential Terms:scleritis, conjunctivitis, uveitis, keratitis, pinguecula, pterygium
Literally: “inflammation upon the hard [coat of the eye]”
CODING AND NUANCES
🏥 ICD-10-CM Codes
Primary Episcleritis (H15.1xx)
Code
Description
H15.101
Unspecified episcleritis, right eye
H15.102
Unspecified episcleritis, left eye
H15.103
Unspecified episcleritis, bilateral
H15.109
Unspecified episcleritis, unspecified eye
H15.111
Episcleritis periodica fugax, right eye
H15.112
Episcleritis periodica fugax, left eye
H15.113
Episcleritis periodica fugax, bilateral
H15.119
Episcleritis periodica fugax, unspecified eye
H15.121
Nodular episcleritis, right eye
H15.122
Nodular episcleritis, left eye
H15.123
Nodular episcleritis, bilateral
H15.129
Nodular episcleritis, unspecified eye
Infectious Etiology
Code
Description
A18.51
Tuberculous episcleritis
⚠️ Coding notes
All H15.1xx codes are 7 characters and valid for HIPAA transactions. Laterality must be specified when documented. If associated with a systemic disease (e.g., rheumatoid arthritis, IBD), code the underlying condition additionally per etiology/manifestation convention.
🔧 CPT Codes
Episcleritis is treated medically (topical NSAIDs, corticosteroids, lubricants), so there are no procedure-specific CPT codes for episcleritis itself. Relevant CPT codes are for the associated E&M and diagnostic services: