DEFINITION of nephrolithotomy

nephrolithotomy is a surgical procedure to remove kidney stones (calculi) through an incision into the kidney or renal pelvis. Nephrolithotomy is the surgical removal of kidney/upper ureteral stones via direct incision, most commonly percutaneous nephrolithotomy (PCNL) where a tract is created through the flank skin to the collecting system under fluoro/ultrasound guidance, dilating to 24-30 Fr for nephroscope access, fragmentation (laser/ultrasonic lithotripsy), and extraction/basketing; reserved for large (>2 cm), staghorn, or complex stones after failed ESWL/ureteroscopy.


ETYMOLOGY of nephrolithotomy

greekNephro-: Greek nephrós (νεφρός) = “kidney.” • Litho-: Greek líthos (λίθος) = “stone.” • -tomy: Greek tomḗ (τομή) = “incision, cutting.” • Literal: “Kidney stone cutting/incision” (coined 19th century).




CPT Coding

Primary Codes (50060-50081):[3][6][2][4][1]

CodeDescription (Stone Size/Complexity)RVU/Notes
50060Nephrolithotomy; complicated/extended pyelolithotomy (open).Open approach.
50080Percutaneous nephrolithotomy/pyelolithotomy ≤2 cm (simple).Includes dilation, lithotripsy, stent/tube.
50081Percutaneous nephrolithotomy/pyelolithotomy >2 cm/complex (staghorn, branching).High complexity; mutually exclusive w/50080.

Access/Dilation Add-ons (if separate):

Modifiers: -22 (increased work), -51 (multiple), -66 (team).[1]

ICD-10-PCS:

  • 0TC03ZZ - Resection kidney stone percutaneous.[7]

Diagnoses: N20.0 (kidney/ureter calculus).[8]

Procedure Types

  • Open Nephrolithotomy (50060): Flank incision; rare (<1% cases).
  • percutaneous Nephrolithotomy (PCNL, 50800/81): Prone/supine; tract via 18G needle → Amplatz dilators → nephroscope; mini-PCNL (14-20 Fr tracts).[2][4]
  • Endourologic: Flexible nephroscopy via tract.[4]

Indications: Stones >2 cm, staghorn, ESWL failure, morbid obesity, abnormal anatomy.[2]

Complications (5-30%): Bleeding (transfusion 1-5%), infection/sepsis (3%), pleural injury (supracostal), colon perforation; Clavien III+ ~10%.[2]

Outcomes: Stone-free rate 75-95% (complex cases lower); hospital stay 1-3 days.

One-Sentence Summary
Nephrolithotomy (Greek nephro-litho--tomykidney-stone-cut”), primarily PCNL (CPT 50080 simple ≤2 cm / 50081 complex >2 cm), surgically extracts large renal calculi (N20.0) via percutaneous flank tract with lithotripsy/stenting for staghorn/ESWL failures.

Med roots Appendix A Prefixes Appendix B Combining Forms Appendix C Suffixes Appendix D Suffix forms