ICD-10-CM N18.5 - Chronic Kidney Disease, Stage 5

Code Description

N18.5 is a billable/specific ICD-10-CM diagnosis code used to identify Chronic Kidney Disease, Stage 5 for reimbursement and clinical documentation purposes. This code represents the most severe stage of chronic kidney disease prior to the classification of End Stage Renal Disease (ESRD). It is effective for the fiscal year October 1, 2025 through September 30, 2026.

Clinical Definition

Chronic Kidney Disease Stage 5 represents kidney failure with severely reduced kidney function. At this stage, the glomerular filtration rate (GFR) is less than 15 mL/min/1.73m². The kidneys are nearly or completely non-functional. Patients at this stage require preparation for renal replacement therapy (dialysis or transplantation) but are not yet on chronic dialysis. If the patient initiates chronic dialysis, the code changes to N18.6.


Code Hierarchy & Tree Structure

ICD-10-CM Code Tree for N18.5

Chapter 14: Diseases of the Genitourinary System (N00-N99)
└── Acute Kidney Failure and Chronic Kidney Disease (N17-N19)
    └── Chronic Kidney Disease (N18)
        ├── N18.1 - Chronic kidney disease, stage 1
        ├── N18.2 - Chronic kidney disease, stage 2 (mild)
        ├── N18.3 - Chronic kidney disease, stage 3 (moderate)
        │   ├── N18.30 - Chronic kidney disease, stage 3 unspecified
        │   ├── N18.31 - Chronic kidney disease, stage 3a
        │   └── N18.32 - Chronic kidney disease, stage 3b
        ├── N18.4 - Chronic kidney disease, stage 4 (severe)
        ├── N18.5 - Chronic kidney disease, stage 5 ← THIS CODE
        ├── N18.6 - End stage renal disease
        └── N18.9 - Chronic kidney disease, unspecified

Parent Code: N18 - Chronic kidney disease (CKD)

Adjacent Codes:

  • Previous: N18.4 - Chronic kidney disease, stage 4 (severe)
  • Next: N18.6 - End stage renal disease

Official Coding Guidelines

Code First Requirements

When coding N18.5, the following conditions must be coded FIRST if documented:

ConditionICD-10-CM Code
Diabetic chronic kidney diseaseE08.22, E09.22, E10.22, E11.22, E13.22
Hypertensive chronic kidney diseaseI12.-, I13.-

Use Additional Code Requirements

The following codes should be added when applicable:

ConditionICD-10-CM Code
Associated cachexiaE88.A
Kidney transplant statusZ94.0
Stage of CKD (when coding hypertensive CKD)N18.1-N18.5, N18.9

Important Coding Notes

  1. Always code the stage of CKD when documented by the provider
  2. Do not code CKD stage based solely on GFR results without provider documentation
  3. If both CKD stage and ESRD are documented, assign code N18.6 only
  4. CKD Stage 5 without dialysis is coded as N18.5. If the patient begins chronic dialysis, update to N18.6
  5. Acute on Chronic: If acute kidney failure is superimposed on chronic kidney disease, code both the acute failure (N17.-) and the chronic stage (N18.5)

Includes & Excludes

Type 1 Excludes (Never Code Together)

CodeDescription
N18.6End stage renal disease (if patient requires chronic dialysis)
N17.-Acute kidney failure (unless coding acute on chronic)

Type 2 Excludes (May Code Together If Clinically Appropriate)

Code RangeDescription
P04-P96Certain conditions originating in the perinatal period
A00-B99Certain infectious and parasitic diseases
O00-O9AComplications of pregnancy, childbirth and the puerperium
Q00-Q99Congenital malformations, deformations and chromosomal abnormalities
E00-E88Endocrine, nutritional and metabolic diseases
S00-T88Injury, poisoning and certain other consequences of external causes
C00-D49Neoplasms
R00-R94Symptoms, signs and abnormal clinical and laboratory findings

Category-Level Excludes (N17-N19)

CodeDescription
P96.0Congenital renal failure
N14.-Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
R39.2Extrarenal uremia / Prerenal uremia
D59.3-Hemolytic-uremic syndrome
K76.7Hepatorenal syndrome
O90.41Postpartum hepatorenal syndrome / Renal failure following labor and delivery
T79.5Posttraumatic renal failure
O00-O07, O08.4Renal failure complicating abortion or ectopic or molar pregnancy
N99.0Renal failure postprocedural

HCC Risk Adjustment Information (2026 CMS-HCC V28)

Hierarchical Condition Category Mapping

AttributeValue
HCC ModelCMS-HCC Version 28 (V28)
HCC CategoryHCC 138
HCC DescriptionChronic Kidney Disease, Stage 4/5
Risk Score ImpactHigh
Model Year2026 (Full V28 Implementation)

V28 Model Changes (2026)

The CMS-HCC Model V28 fully implemented in 2026 includes 115 HCC categories to better stratify conditions by severity. Key changes affecting N18.5:

  • Consolidated CKD Staging: Stage 4 and Stage 5 often map to the same HCC category (HCC 138) in V28, reflecting similar resource utilization risk prior to dialysis.
  • Higher risk scores for documented Stage 5 CKD vs. unspecified CKD
  • Requires annual recapture for Medicare Advantage risk adjustment
  • eGFR documentation strongly recommended to support stage assignment

HCC Coding Best Practices

  1. Document eGFR values to support CKD stage assignment (GFR < 15)
  2. Capture CKD stage annually for risk adjustment purposes
  3. Link CKD to underlying etiology (diabetes, hypertension, etc.)
  4. Avoid unspecified CKD (N18.9) when stage is known
  5. Monitor dialysis status: If dialysis initiates, update to N18.6 immediately as HCC mapping may change for ESRD populations

MS-DRG Mapping (Inpatient)

Primary MS-DRG Assignments

N18.5 maps to the following Medicare Severity Diagnosis-Related Groups for fiscal year 2026 (MS-DRG V43.0):

MS-DRGDescriptionMDCRelative WeightCC/MCC Status
682Renal Failure with MCC111.4810Major Complication/Comorbidity
683Renal Failure with CC110.8758Complication/Comorbidity
684Renal Failure without CC/MCC110.6003No CC/MCC

Additional MS-DRG Mappings

MS-DRGDescription
008Simultaneous pancreas and kidney transplant
019Simultaneous pancreas and kidney transplant with hemodialysis

MDC Information

  • MDC 11: Diseases & Disorders of the Kidney & Urinary Tract
  • Relative Weight Range: 0.6003 - 1.4810 (depending on CC/MCC presence)
  • Geometric Mean Length of Stay: Varies by facility and patient acuity

CC/MCC Designation

  • N18.5 is classified as a CC (Complication/Comorbidity)
  • When paired with other qualifying conditions, may contribute to MCC assignment
  • CC status affects hospital reimbursement under IPPS
  • Stage 5 CKD is often considered more severe than Stage 4, potentially influencing CC/MCC logic depending on specific payer policies, though officially both are CCs in the DRG grouper logic unless specific complications arise

Note

ICD-10 diagnosis codes do not have wRVUs. The following CPT codes represent services typically billed when N18.5 is the primary diagnosis.

Evaluation & Management (E/M) Codes

CPT CodeDescriptionSettingwRVU (2026)Assistant Payable
99202Office/outpatient E/M, new patient, low complexityOffice0.70No
99203Office/outpatient E/M, new patient, moderate complexityOffice1.30No
99204Office/outpatient E/M, new patient, high complexityOffice1.92No
99205Office/outpatient E/M, new patient, high complexityOffice2.74No
99212Office/outpatient E/M, established patient, low complexityOffice0.48No
99213Office/outpatient E/M, established patient, moderate complexityOffice0.88No
99214Office/outpatient E/M, established patient, high complexityOffice1.36No
99215Office/outpatient E/M, established patient, high complexityOffice1.92No
99221Initial hospital care, low complexityInpatient1.42Yes
99222Initial hospital care, moderate complexityInpatient2.11Yes
99223Initial hospital care, high complexityInpatient3.00Yes
99231Subsequent hospital care, low complexityInpatient0.74Yes
99232Subsequent hospital care, moderate complexityInpatient1.26Yes
99233Subsequent hospital care, high complexityInpatient1.88Yes
99238Hospital discharge day management, ≤30 minInpatient0.81No
99239Hospital discharge day management, >30 minInpatient1.28No

Nephrology-Specific CPT Codes

CPT CodeDescriptionwRVU (2026)Assistant Payable
90951ESRD services, patient <2 years, 4+ face-to-face visits/month3.58No
90952ESRD services, patient 2-11 years, 4+ face-to-face visits/month3.26No
90953ESRD services, patient 12-19 years, 4+ face-to-face visits/month2.94No
90954ESRD services, patient 20+ years, 4+ face-to-face visits/month2.67No
90955ESRD services, patient <2 years, 2-3 face-to-face visits/month2.39No
90956ESRD services, patient 2-11 years, 2-3 face-to-face visits/month2.17No
90957ESRD services, patient 12-19 years, 2-3 face-to-face visits/month1.96No
90958ESRD services, patient 20+ years, 2-3 face-to-face visits/month1.78No
90959ESRD services, patient <2 years, 1 face-to-face visit/month1.19No
90960ESRD services, patient 2-11 years, 1 face-to-face visit/month1.08No
90961ESRD services, patient 12-19 years, 1 face-to-face visit/month0.98No
90962ESRD services, patient 20+ years, 1 face-to-face visit/month0.89No
90963ESRD services, patient <2 years, less than 1 visit/month0.60No
90964ESRD services, patient 2-11 years, less than 1 visit/month0.54No
90965ESRD services, patient 12-19 years, less than 1 visit/month0.49No
90966ESRD services, patient 20+ years, less than 1 visit/month0.45No

Note: ESRD codes (90951-90966) are strictly for patients with N18.6 (End Stage Renal Disease) on dialysis. Patients with N18.5 are billed using standard E/M codes (99202-99215) until dialysis initiates.

Consultation Codes (If Payer Accepts)

CPT CodeDescriptionwRVU (2026)Assistant Payable
99242Office consultation, new patient, low complexity1.09No
99243Office consultation, new patient, moderate complexity1.62No
99244Office consultation, new patient, high complexity2.36No
99245Office consultation, new patient, high complexity3.09No
99252Inpatient consultation, low complexity1.49Yes
99253Inpatient consultation, moderate complexity2.18Yes
99254Inpatient consultation, high complexity3.06Yes
99255Inpatient consultation, high complexity3.94Yes

Assistant Surgeon Payability

Code TypeAssistant Payable (80/82)Co-Surgeon (62)Team Surgery (66)
E/M CodesVaries by code (see above)N/AN/A
ESRD CodesNoN/AN/A
ConsultationYes (if payer accepts)N/AN/A

Clinical Documentation Requirements

Required Documentation Elements

To support N18.5, the following must be documented:

  1. Explicit CKD Stage 5 diagnosis by treating provider
  2. eGFR values supporting stage assignment (GFR < 15 mL/min/1.73m²)
  3. Duration of kidney disease (chronic = 3+ months)
  4. Underlying etiology (diabetes, hypertension, glomerulonephritis, etc.)
  5. Complications related to CKD (anemia, bone disease, electrolyte abnormalities, uremia)
  6. Treatment plan including preparation for renal replacement therapy (dialysis access planning, transplant evaluation)
  7. Dialysis Status: Explicit documentation that patient is NOT yet on chronic dialysis (otherwise code N18.6)

Laboratory Value Support

ParameterStage 5 Range
eGFR< 15 mL/min/1.73m²
Serum CreatinineSignificantly Elevated
BUNSignificantly Elevated
HemoglobinOften shows anemia of CKD
PhosphorusOften elevated (hyperphosphatemia)
CalciumMay be low (hypocalcemia)
PTHOften significantly elevated (secondary hyperparathyroidism)
PotassiumRisk of hyperkalemia

Documentation Tips

  • Avoid coding CKD stage based on lab values alone without provider diagnosis
  • Query provider if stage is not explicitly documented
  • Link CKD to diabetes/hypertension when clinically related
  • Document complications for complete risk adjustment capture
  • Clarify Dialysis Status: Ensure documentation distinguishes between pre-dialysis Stage 5 (N18.5) and ESRD on dialysis (N18.6)

Coding Examples

Example 1: CKD Stage 5 Due to Diabetes

Clinical Scenario: 68-year-old male with Type 2 diabetes mellitus and CKD Stage 5 (not on dialysis)

DiagnosisICD-10-CM Code
Type 2 diabetes mellitus with diabetic chronic kidney diseaseE11.22
Chronic kidney disease, stage 5N18.5

Coding Note: Code E11.22 first, then N18.5 as additional code


Example 2: Hypertensive CKD Stage 5

Clinical Scenario: 72-year-old female with hypertension and CKD Stage 5 (not on dialysis)

DiagnosisICD-10-CM Code
Hypertensive chronic kidney disease with stage 5 CKDI12.9
Chronic kidney disease, stage 5N18.5

Coding Note: Code I12.9 first, then N18.5 to specify stage


Example 3: CKD Stage 5 with Anemia

Clinical Scenario: 65-year-old male with CKD Stage 5 and anemia

DiagnosisICD-10-CM Code
Chronic kidney disease, stage 5N18.5
Anemia in chronic kidney diseaseD63.1

Coding Note: Both codes may be assigned when both conditions are documented


Example 4: Hypertensive Heart & Kidney Disease Stage 5

Clinical Scenario: 70-year-old with hypertensive heart disease and CKD Stage 5

DiagnosisICD-10-CM Code
Hypertensive heart and chronic kidney disease without heart failure, stage 5I13.10
Chronic kidney disease, stage 5N18.5

Coding Note: Code I13.10 first, then N18.5


Example 5: CKD Stage 5 with Kidney Transplant Status

Clinical Scenario: Patient with CKD Stage 5 and prior kidney transplant (graft failure)

DiagnosisICD-10-CM Code
Chronic kidney disease, stage 5N18.5
Kidney transplant statusZ94.0

Coding Note: Use additional code Z94.0 to identify transplant status. If graft failure is documented, code transplant complication first.


Common Coding Errors to Avoid

ErrorCorrect Approach
Coding N18.5 when patient is on chronic dialysisCode N18.6 (ESRD) instead
Assigning stage based on GFR without provider documentationQuery provider for explicit stage documentation
Coding N18.9 when stage is documentedUse specific stage code (N18.1-N18.6)
Missing underlying etiology (diabetes/hypertension)Code underlying condition first per guidelines
Failing to capture CKD annually for HCCDocument and code CKD stage at least once per calendar year
Coding both N18.5 and N18.6 togetherOnly code N18.6 if ESRD is present
Using ESRD CPT codes (90951-90966) for Stage 5Use standard E/M codes until dialysis initiates

Quality Measures & HEDIS

MeasureDescription
KEDKidney Disease: Evaluation of Urine Protein
KDCKidney Disease: Communication with the Physician Following Outpatient Dialysis
BPDBlood Pressure Control
CDCControlling High Blood Pressure
PREPreoperative Care (for access planning)

Documentation for Quality Reporting

  • Urinary protein testing should be documented for CKD patients
  • Blood pressure control targets should be noted
  • Medication reconciliation including ACE inhibitors/ARBs when appropriate
  • Nephrology referral documentation for Stage 5 CKD (should already be established)
  • Dialysis Education: Document education regarding modalities (hemodialysis vs peritoneal)
  • Vascular Access: Document planning for fistula/graft placement

ICD-9-CM Crosswalk

ICD-10-CMICD-9-CMDescription
N18.5585.5Chronic kidney disease, stage V

Mapping Type: Direct match with no additional qualifiers


Code History

Fiscal YearEffective DateStatus
FY 20262025-10-01No Change
FY 20252024-10-01No Change
FY 20242023-10-01No Change
FY 20232022-10-01No Change
FY 20222021-10-01No Change
FY 20212020-10-01No Change
FY 20202019-10-01No Change
FY 20192018-10-01No Change
FY 20182017-10-01No Change
FY 20172016-10-01No Change
FY 20162015-10-01No Change
FY 20152015-10-01New Code (First year of ICD-10-CM implementation)

CKD Stage Codes

CodeDescriptionGFR Range
N18.1CKD Stage 1≥90
N18.2CKD Stage 2 (mild)60-89
N18.30CKD Stage 3 unspecified30-59
N18.31CKD Stage 3a45-59
N18.32CKD Stage 3b30-44
N18.4CKD Stage 4 (severe)15-29
N18.5CKD Stage 5< 15
N18.6End Stage Renal DiseaseOn dialysis
N18.9CKD, unspecifiedNot documented

Common Comorbidity Codes

CodeDescription
D63.1Anemia in chronic kidney disease
E88.ACachexia
Z94.0Kidney transplant status
Z99.2Dependence on renal dialysis
I10Essential (primary) hypertension
E11.9Type 2 diabetes mellitus without complications
N17.9Acute kidney failure, unspecified (if acute on chronic)

Clinical Pearls

  1. Stage 5 CKD represents kidney failure with GFR < 15 mL/min/1.73m²
  2. Not ESRD yet: Distinguish carefully between Stage 5 (N18.5) and ESRD (N18.6). The dividing line is chronic dialysis or transplant.
  3. Nephrology referral is mandatory at Stage 5 for renal replacement planning
  4. Medication adjustments are critical due to minimal kidney function
  5. Cardiovascular risk is extremely elevated in Stage 5 CKD
  6. Annual HCC capture is essential for Medicare Advantage risk adjustment
  7. Provider documentation of stage is required; cannot code from labs alone
  8. Transition to ESRD (N18.6) occurs when dialysis begins or transplant is needed
  9. Uremic Symptoms: Watch for documentation of uremic symptoms (nausea, pericarditis, encephalopathy) which may impact DRG assignment

See Also

  • N18 - Chronic kidney disease (CKD)
  • N18.4 - Chronic kidney disease, stage 4 (severe)
  • N18.6 - End stage renal disease
  • I12.9 - Hypertensive chronic kidney disease
  • E11.22 - Type 2 diabetes with diabetic chronic kidney disease
  • D63.1 - Anemia in chronic kidney disease
  • Z94.0 - Kidney transplant status
  • MS-DRG 682 - Renal Failure with MCC
  • MS-DRG 683 - Renal Failure with CC
  • MS-DRG 684 - Renal Failure without CC/MCC

Last Updated: March 12, 2026 Code Status: Active Fiscal Year: 2026 (October 1, 2025 - September 30, 2026)