DEFINITION of fistula

fistula is an abnormal, tube-like passage that forms a connection between two internal organs, between two blood vessels, or between an internal organ and the exterior of the body (the skin). Unlike a sinus tract, which is a blind-ending channel that opens to only one surface, a fistula connects two distinct epithelialized surfaces. The underlying pathological mechanism typically involves chronic inflammation, infection (such as an unresolved abscess that ruptures into adjacent structures), surgical trauma, ischemic injury, or penetrating trauma, which causes tissue necrosis and subsequent abnormal healing. While the vast majority of fistulas are pathological (e.g., anal fistula, vesicovaginal fistula), they can also be physiological/iatrogenic when surgically created for therapeutic purposes (e.g., an arteriovenous fistula created for hemodialysis access). The clinically relevant subtypes most commonly encountered in coding include anal fistulas (K60.3), vesicovaginal fistulas (N82.0), enterocutaneous fistulas (K63.2), and surgically created arteriovenous fistulas (Z99.2 for presence/dependence). Fistulas are commonly confused with fissures; however, a fissure is simply a tear or crack in the mucosal lining or skin, whereas a fistula is a complete tunnel connecting two separate spaces.


ETYMOLOGY of fistula

latin

ComponentOriginMeaning
fistul-Latin fistula (fistula)“pipe,” “tube,” “flute,” “ulcer”
-aLatin -a (-a)Noun-forming suffix — “state or condition of”

The word entered English in the 1390s as fistula (noun), borrowed directly from Latin fistula — literally “pipe, tube, or ulcer.” The root fistula (“pipe/tube”) connects fistula to the entire fistul- family: fistulotomy (surgical incision of a pipe/tract), fistulectomy (surgical excision of a pipe/tract), and fistulization (the process of forming an abnormal tract).


🔀 ALIASES / ALTERNATE TERMS

  • Fistulous (adjective form — e.g., “fistulous tract,” “fistulous disease,” “fistulous communication”)
  • Abnormal tract (lay and clinical synonym; often used in radiology reports describing contrast extravasation)
  • Incomplete fistula / Sinus tract (a partial or blind-ending tract that has not yet connected to a second surface; often a precursor to a true fistula)
  • Arteriovenous fistula (AVF) (vascular connection between an artery and a vein; can be congenital, acquired via trauma, or surgically created for dialysis)
  • Enterocutaneous fistula (ECF) (abnormal connection between the intestinal tract and the skin; highly morbid, often a complication of abdominal surgery)
  • Vesicovaginal fistula (VVF) (abnormal connection between the bladder and the vagina; causes continuous urinary incontinence, often obstetric or surgical in origin)
  • Colovesical fistula (abnormal connection between the colon and the bladder; commonly caused by diverticulitis, presenting with pneumaturia or fecaluria)
  • Tracheoesophageal fistula (TEF) (connection between the trachea and esophagus; can be congenital [Q39.x] or acquired [J86.0])
  • Anal fistula / Fistula-in-ano (epithelialized track connecting the anal canal to the perianal skin; almost always arises from a cryptoglandular abscess)
  • Branchial cleft fistula (congenital anomaly of the neck; Q18.0)
  • Carotid-cavernous fistula (CCF) (abnormal communication between the carotid artery and the cavernous sinus; presents with pulsatile exophthalmos)
  • Lacrimal fistula (abnormal tract from the lacrimal sac or gland to the skin surface; H04.61x)

đź”— RELATED TERMS

  • Anastomosis — the opposite of a pathological fistula in intent; a deliberate, surgically created connection between two tubular structures (e.g., bowel loops or blood vessels) to restore continuity.
  • Sinus tract — shares the characteristic of an abnormal channel, but is a blind-ending tract that opens to only one epithelial surface (often draining an underlying abscess cavity).
  • Fissure — a linear tear or crack in the mucosal lining (e.g., anal fissure, K60.2); often confused with a fistula but lacks a tunneling tract.
  • Abscess — a localized collection of pus; the rupture and incomplete healing of an abscess is the primary physiological mechanism that creates a fistulous tract.
  • Epithelialization — the cellular mechanism where epithelial cells migrate to line the abnormal tract, preventing it from closing spontaneously and making the fistula chronic.
  • Crohn’s disease — inflammatory bowel disease characterized by transmural inflammation, making it a primary causative disease entity for enteroenteric, enterocutaneous, and perianal fistulas (K50.x).
  • Diverticulitis — inflammation of colonic outpouchings; the most common underlying disease entity causing colovesical fistulas (K57.x).
  • Fistulogram / Sinogram — primary diagnostic fluoroscopic procedure involving the injection of radiopaque contrast into the external opening to map the tract’s course and internal opening.

CODING CORNER

🏥 ICD-10-CM CODES

Gastrointestinal & Anal Fistulas (General Surgery / GI)

CodeDescription
K60.3Anal fistula
K60.4Rectal fistula
K60.5Anorectal fistula
K63.2Fistula of intestine (includes enterocutaneous, enteroenteric)
K31.6Fistula of stomach and duodenum
K11.4Fistula of salivary gland
K83.3Fistula of bile duct
K50.013Crohn’s disease of small intestine with fistula
K50.113Crohn’s disease of large intestine with fistula

Genitourinary Fistulas (Urology / Gynecology)

CodeDescription
N82.0Vesicovaginal fistula
N82.1Other female intestinal-genital tract fistulae
N82.2Fistula of vagina to small intestine
N82.3Fistula of vagina to large intestine
N82.4Other female intestinal-genital tract fistulae
N82.5Female genital tract-skin fistulae
N32.1Vesicointestinal fistula (includes colovesical fistula)
N36.0Urethral fistula

Head, Neck, Ocular & Respiratory Fistulas (ENT / Ophthalmology)

CodeDescription
H04.611Fistula of lacrimal gland, right lacrimal gland
H04.612Fistula of lacrimal gland, left lacrimal gland
H04.613Fistula of lacrimal gland, bilateral lacrimal glands
Q18.0Sinus, fistula and cyst of branchial cleft
J86.0Pyothorax with fistula
J95.01Hemorrhage from tracheostomy stoma (often associated with tracheo-innominate fistula)
Q39.1Atresia of esophagus with tracheoesophageal fistula
Q39.2Congenital tracheoesophageal fistula without atresia

Vascular & Iatrogenic Fistulas (Vascular / Nephrology)

CodeDescription
I77.0Arteriovenous fistula, acquired
Q27.30Arteriovenous malformation, site unspecified
Z99.2Dependence on renal dialysis (used to indicate presence of functioning AV fistula)
T82.518ABreakdown (mechanical) of other vascular grafts and blood vessel prostheses, initial encounter (used for AV fistula failure)
T82.598AOther mechanical complication of other vascular grafts and blood vessel prostheses, initial encounter

CPT CodeDescription
46270Surgical treatment of anal fistula (fistulotomy/fistulectomy); subcutaneous
46275Surgical treatment of anal fistula (fistulotomy/fistulectomy); intersphincteric
46280Surgical treatment of anal fistula (fistulotomy/fistulectomy); complex or multiple, with or without placement of seton
46282Surgical treatment of anal fistula (fistulotomy/fistulectomy); second stage
57320Closure of vesicovaginal fistula; vaginal approach
57330Closure of vesicovaginal fistula; transvesical and vaginal approach
51900Closure of vesicovaginal fistula, abdominal approach
44660Closure of enterovesical fistula; without intestinal or bladder resection
44661Closure of enterovesical fistula; with intestine and/or bladder resection
36821Arteriovenous anastomosis, open; direct, any site (e.g., Cimino type) (Creation of AV fistula for dialysis)
20500Injection of sinus tract; therapeutic (eg, for closure)
20501Injection of sinus tract; diagnostic (sinogram) (Requires radiological supervision and interpretation code 76080)

⚠️ Coding Note: When coding fistulas in the inpatient profee setting, sequencing depends heavily on the etiology and the reason for admission. If the fistula is a manifestation of an underlying disease (e.g., Crohn’s disease, diverticulitis, or radiation cystitis), the underlying condition is typically sequenced first, followed by the specific fistula code. A common undercoding alert involves colovesical fistulas; coders often see “pneumaturia” or “fecaluria” documented but fail to query for the presence of a colovesical fistula (N32.1) and its underlying cause (e.g., K57.20 Diverticulitis). For surgically created AV fistulas for dialysis, do not code them as a complication or disease unless they are failing, infected, or bleeding; a functioning AV fistula is captured simply by Z99.2 (Dependence on renal dialysis). When coding surgical closures (e.g., CPT 44661), ensure the operative report clearly documents whether a resection of the bowel or bladder was required, as this significantly impacts the RVU and code selection.




Med terms dictionary Appendix A Prefixes Appendix B Combining Forms Appendix C Suffixes Appendix D Suffix forms